But Wyle succeeded. Since the show’s end, Wyle has gone on to star in a handful of guest roles in the TV series Angie Tribeca, Drunk History, Lab Rats and more. The 46-year old also scored several leading roles in the sci-fi drama Falling Skies and The Librarians where he currently stars opposite Rebecca Romijn and John Larroquette.
ER gave movie star George Clooney a major career kick-start. The pre-McDreamy doctor attracted quite the fan base with his good looks and likable personality in his role as Doug Ross. The actor only appeared in 109 episodes of ER compared to Wyle’s 254 episode stint, but definitely made his mark and managed to be one of the most memorable ER characters.
Clooney, now 56-years old, went on to star in a slew of roles that made millions. From Up In The Air to the Oceans franchise, Clooney’s most recent work includes the movie Money Monster and Hail! Ceaser. The new father also works behind the camera, producing a number of hugely successful projects like Argo, The American and more.